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Buprenorphine

Buprenorphine is a semi-synthetic narcotic derived from thebaine and is currently being investigated for the treatment of narcotic addiction

Like methadone and LAAM, buprenorphine is potent (30 to 50 times the analgesic potency of morphine), has a long duration of action, and does not need to be injected. The products under development are sublingual tablets. Unlike the other treatment drugs, this drug produces far less respiratory depression and is thought to be safer in overdose. The drug is currently available in the United States as an injectable Schedule V narcotic analgesic (Buprenex®) for human and veterinary use.

Source: DEA – Schedule III narcotic medications Suboxone® tablets (buprenorphine hydrochloride and naloxone hydrochloride) received FDA approval for the treatment of opioid addiction.

Both buprenorphine and methadone are medications used for detoxification, short- and long-term opioid replacement therapy. Buprenorphine has the advantage of being only a partial agonist; hence negating the potential for life-threatening respiratory depression in cases of abuse.[4] Studies show the effectiveness of this drug and methadone are almost identical, and largely share adverse-effect profiles apart from more sedation among methadone users. At low doses from 2 to 6 mg, however, the drug has a lower retention rate than low doses of 40 mg or less of methadone.

Other Sources:

Sublingual and Buccal
Buprenorphine and the combination of buprenorphine and naloxone are used to treat opioid dependence (addiction to opioid drugs, including heroin and narcotic painkillers). Buprenorphine is in a …
https://www.nlm.nih.gov/medlineplus/druginfo/meds/a605002.html – Drugs and Supplements
Pregnancy Reduces Neonate Distress From the National Institutes of Health(National Institute on Drug Abuse)
… Notes » Treatment » Buprenorphine During Pregnancy Reduces Neonate Distress Buprenorphine During Pregnancy Reduces Neonate Distress Email Facebook Twitter …
https://www.drugabuse.gov/…ring-pregnancy-reduces-neonate-distress – External Health Links
3. Transdermal Patch
Buprenorphine patches are used to relieve severe pain in people who are expected to need pain medication … Transdermal buprenorphine comes as a patch to apply to the skin. The patch is usually applied to the skin …
https://www.nlm.nih.gov/medlineplus/druginfo/meds/a613042.html – Drugs and Supplements
Facts about Treatment of Opioid Addiction (Substance Abuse and Mental Health Services Administration) – PDF
the facts about BUPRENORPHINE for Treatment of Opioid Addiction U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Substance Abuse and Mental Health Services Administration …

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