Fioricet and Esgic are brand names of a combination of butalbital (a barbiturate), acetaminophen and caffeine which is indicated for the treatment of tension headaches, muscle contraction headaches and post-dural puncture headaches. Although not indicated, they are commonly used to treat migraines and other pain related ailments.

More information in the Prescription Drug Booklet

Other Sources:

List of Confused Drug Names (Institute for Safe Medication Practices) – PDF

… Fastin (dietary supplement) Femara Femhrt fenta NYL Fetzima Fioricet Fiorinal flavox ATE Flonase Floranex Florastor Florinef Florinef … Fastin ( phentermine) Femhrt Femara SUF entanil Farxiga Fiorinal fluvoxa MINE Flovent Florinef Florinef Floranex Florastor Flonase … – External Health Links

Headache Causes and Diagnosis in Adults (Beyond the Basics)(UpToDate)
… the following: ● If possible, avoid butalbital combinations (Fiorinal®, Esgic®) and narcotics completely. ● Do not use triptans ( ……s-in-adults-beyond-the-basics?view=print – External Health Links

State Estimates of Nonmedical Use of Prescription Pain Relievers(Substance Abuse and Mental Health Services Administration) – PDF
… were (4) codeine; (5) Demerol®; (6) Dilaudid®; (7) Fioricet®; (8) Fiorinal®; (9) hydrocodone; (10) methadone; (11) morphine; ( …
Other Sources

Drug Identification Guide

CDC Facts

CDC Addiction Info

CDC Overdose Stats

CDC Substance Treatment

Whitehouse Drug-Free Communities

Samhsa Workplace Programs


Federal Register Codification

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