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Orlistat

Xenical (orlistat 120mg) was approved as a prescription product by FDA in 1999 for obesity management in conjunction with a reduced calorie diet, and to reduce the risk of regaining weight after prior weight loss.

Orlistat (prescription and nonprescription) is used with an individualized low-calorie, low-fat diet and exercise program to help people lose weight. Prescription orlistat is used in overweight people who may also have high blood pressure, diabetes, high cholesterol, or heart disease. Orlistat is also used after weight-loss to help people keep from gaining back that weight. Orlistat is in a class of medications called lipase inhibitors. It works by preventing some of the fat in foods eaten from being absorbed in the intestines. This unabsorbed fat is then removed from the body in the stool.

Orlistat may cause side effects. The most common side effect of orlistat is changed in bowel movement (BM) habits. This generally occurs during the first weeks of treatment; however, it may continue throughout your use of orlistat. Tell your doctor if any of these symptoms are severe or do not go away:

-oily spotting on underwear or on clothing
-gas with oily spotting
-urgent need to have a bowel movement
-loose stools
-oily or fatty stools
-increased number of bowel movements
-difficulty controlling bowel movements
-pain or discomfort in the rectum (bottom)
-stomach pain
-irregular menstrual periods
-headache
-anxiety

Other Sources:

How Are Overweight and Obesity Treated? From the National Institutes of Health (National Heart, Lung, and Blood Institute) 

… raise the risk of heart attack and stroke. Orlistat (Xenical ® and Alli ® ) Orlistat (Xenical ® ) causes a weight loss between 5 and 10 … 6 months of taking the medicine. People taking Xenical need regular checkups with their doctors, especially during …
www.nhlbi.nih.gov/health/health-topics/topics/obe/treatment – External Health Links

Weight-loss medicines
ORLISTAT (XENICAL AND ALLI) Orli

Other Sources

Drug Identification Guide

CDC Facts

CDC Addiction Info

CDC Overdose Stats

CDC Substance Treatment

Whitehouse Drug-Free Communities

Samhsa Workplace Programs

Drug-Free

Federal Register Codification.

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